The teleportation trick can also be used to escape a Curse Room without taking damage. This trick is particularly useful for The Lost. Upon teleportation, Isaac is granted with a short invulnerability period which can be abused to trigger the Blood Donation Machine and Devil Beggar without losing health by placing a portal just next to it, teleporting, and touching the Donation Machine or Beggar in the same move.This item can be used to escape a Challenge Room or the Boss Rush.Devil Room, Angel Room, I AM ERROR room, Crawl Space, Boss Rush, Black Market, Mega Satan room, or ? portal room), Isaac will not be able to enter the portal. However, if a portal leads to a room with a negative grid index (i.e.
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